Hilterapia®: From molecular and cellular effects to clinical studies

T. Viliani, F. Cialdai, C. Risaliti, M. Monici
Energy For Health [22], 2022

Laser therapy has been widely used in many different fields of medicine and has proved to be effective in various pathologic conditions through its anti-inflammatory, anti-edema, and analgesic effects. Despite the richness of literature and the numerous clinical trials that prove the effectiveness of phototherapy, the molecular and cellular mechanisms underlying the therapeutic effects induced by laser emissions of different wavelengths are not completely understood. The study these molecular mechanisms is rather complex due to the different characteristics of the various tissues and body areas (in particular, the different optical properties) and the variety of parameters used in clinical trials, such as wavelength, continuous or pulsed mode, frequency, time of exposure. The aim of this review is to focus on the Nd:YAG laser source used for Hiltherapy and to analyze different studies, both preclinical research and clinical applications, in order to help understand the mechanisms of action of this laser source and the therapeutic effects when it is applied in clinics.